TWINE Effect, by TWINE Medicals, is a lipolysis treatment that reduces localized fat without surgery. It is a fat-dissolving injectable used on areas such as the abdomen, flanks, knees, and back — where stubborn fat pockets persist despite diet and exercise. The injectable contains active ingredients (phosphatidylcholine and deoxycholate) that break down fat cells, which the body then clears over time. It is not a weight-loss treatment.

Benefits

  • Non-surgical fat reduction for localized areas
  • Targets stubborn pockets such as abdomen, flanks, knee fat, and back
  • Minimal downtime — most people return to normal activities quickly
  • Can be used alongside other treatments
  • Destroyed fat cells are gone permanently

Who it’s for

Adults with localized, pinchable fat pockets (for example the abdomen, flanks, knees, or back) that are stable and have been resistant to diet and exercise. It is not appropriate for general weight loss or for people with large areas of fat; results vary. It is not suitable during pregnancy, with an active infection in the area, or where there are certain conditions that affect fat metabolism.

What to expect

We start with a consultation and assessment to measure the area, discuss goals, and agree a plan. The injectable is placed into the target fat using a series of small injections; the session takes about 30–60 minutes depending on the area. Expect tenderness, swelling, and bruising afterward; fat loss is gradual over 4–8 weeks. Typically 2–4 sessions per area, 3–4 weeks apart, are needed.

Typically 2–4 sessions per area, 3–4 weeks apart.

Before & after your visit

  • Before: Tell us about previous fat-reduction treatments, allergies, and medications. Wear loose clothing; avoid caffeine and nicotine (if possible) before the session.
  • After: Expect swelling and tenderness; avoid strenuous exercise for 48 hours. A compression garment may be suggested.
  • Downtime: Minimal, but expect swelling for 1–2 weeks.
  • Results: Gradual improvement over 4–8 weeks; results improve across the series.
  • Duration: Destroyed fat cells are gone permanently, but remaining cells can grow if weight is gained.
  • Risks: Temporary swelling, bruising, pain, or numbness; rarely, uneven results or skin irritation. Your practitioner will discuss risks in detail at consultation.

Frequently asked questions

Does it hurt?
The numbing helps; the injections feel like small pinches. Swelling and soreness afterwards are expected.

How many sessions will I need?
Typically 2–4 sessions per area, 3–4 weeks apart — the exact number depends on the size of the pocket and your goals.

Is the consultation fee credited?
The consultation is $50.

About the brand: Jamila Medical

Our advanced regenerative skin and body treatments from Jamila Medical — the Canadian medical-aesthetics house behind Res Novae, TWINE, and Wonderm. Jamila Medical is the brand behind these product lines.

Product information: Jamila Medical ↗

Price & booking

From $650 per area.

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